About me
I received my Masters degree in Biomedical Engineering at the University Paul Sabatier, Toulouse, France and completed 2 internships at the MNI before taking a job as a research engineer for Dr. Catherine Limperopoulos’s lab. My role is to adapt and develop minctools for pediatric subjects, in order to accomplish volumetric and connectivity studies in fetal, neonatal, premature, and mature infant brains. At the same time, I develop tools to classify fetal and neonatal tissues, and also to improve the 2D registration of fetal MR images. I am now doing my PhD with Dr. Louis Collins, on brain atrophies in MS.

Interest

  • Image processing
  • Registration
  • Classification
  • Surfaces
  • Atlas

Project
Brain atrophy measure

Favorite Links

Publications

Published or in press refereed papers:

  • “Non-local means inpainting of MS lesions in longitudinal image processing”, Nicolas Guizard, Kunio Nakamura, Pierrick Coupé, Vladimir S. Fonov, Douglas L. Arnold, D. Louis Collins, Frontiers in Neuroscience, accepted, 2015.
  • “Rotation-invariant multi-contrast non-local means for MS lesion segmentation”, Nicolas Guizard, Pierrick Coupé, Vladimir Fonov, Jose V. Manjon, Douglas L. Arnold, D. Louis Collins. Neuroimage: Clinical, 2015, doi:10.1016/j.nicl.2015.05.001
  • “Improving recorded volume in mesial temporal lobe by optimizing stereotactic intracranial electrode implantation planning”, R. Zelmann, S. Beriault, M. M. Marinho, K. Mok, J. A. Hall, N. Guizard, C. Haegelen, A. Olivier, G. B. Pike, D. L. Collins , International Journal of Computer Assisted Radiology and Surgery, 2015, doi:10.1007/s11548–015–1165–6
  • “Investigation of morphometric variability of subthalamic nucleus, red nucleus and substantia nigra in advanced Parkinson’s disease patients using automatic segmentation and PCA-based analysis”, Yimming Xiao, Pierre Jannin, Tiziano D’Albis, Nicolas Guizard, Claire Haegelen, Florent Lalys, Marc Verin, D. Louis Collins, HBM, 2014, doi: 10.1002/hbm.22478
  • “Jacobian integration method increases the statistical power to measure gray matter atrophy in multiple sclerosis”, Kunio Nakamura, Nicolas Guizard, Vladimir S. Fonov, Sridar Narayanan, D. Louis Collins, Douglas L. Arnold, NeuroImage, 2014, doi: 10.1016/j.nicl.2013.10.015
  • “A new method for structural volume analysis of longitudinal brain MRI data and its application in studying the growth trajectories of anatomical brain structures in childhood”, Berengere M Aubert-Broche, Vladimir Fonov, Daniel Garcia-Lorenzo, Abderazzak Mouiha, Nicolas Guizard, Pierrick Coupe, Simon Eskildsen, D Louis Collins, NeuroImage, 2013, doi: 10.1016/j.neuroimage.2013.05.065
  • “Injury to the Premature Cerebellum: Outcome is Related to Remote Cortical Development”, Catherine Limperopoulos, Gevorg Chilingaryan, Nancy Sullivan, Nicolas Guizard, Richard L. Robertson, Adré J. du Plessis, Cerebral Cortex, November, 2012
  • “Regional cerebellar volumes predict functional outcome in children with cerebellar malformations”, Marie-Eve Bolduc, Adre J du Plessis, Nancy Sullivan, Nicolas Guizard, Xun Zhang, Richard L Robertson, Catherine Limperopoulos, The Cerebellum, Volume 11, Issue 2, Pages 531–542, 2012
  • “Automated segmentation of basal ganglia and deep brain structures in MRI of Parkinson’s disease”, Claire Haegelen, Pierrick Coupé, Vladimir Fonov, Nicolas Guizard, Pierre Jannin, Xavier Morandi, D Louis Collins, 1–12
  • “A New Framework for Analyzing Structural Volume Changes of Longitudinal Brain MRI Data”, Bérengère Aubert-Broche, Vladimir Fonov, Daniel García-Lorenzo, Abderazzak Mouiha, Nicolas Guizard, Pierrick Coupé, Simon Eskildsen, Louis D. Collins, Spatio-temporal Image Analysis for Longitudinal and Time-Series Image Data, 2012
  • “Robust individual template pipeline for longitudinal MR images”, Nicolas Guizard, Vladimir Fonov, Daniel García-Lorenzo, Bérengère Aubert-Broche, Simon Eskildsen, D Collins, Spatio-temporal Image Analysis for Longitudinal and Time-Series Image Data, 2012
  • “BEaST: Brain Extraction based on nonlocal Segmentation Technique”, S.F. Eskildsen, P. Coupe, V. Fonov, J.V. Manjon, K. K. Leung, N. Guizard, S. N. Wassef, L.R. Østergaard, D.L. Collins, and the Alzheimer’s Disease Neuroimaging Initiative, Multi-Atlas Labeling and Statistical Fusion, NeuroImage, Vol. 59, No. 3. (16 February 2012), pp. 2362–2373
  • “Normative fetal brain growth by quantitative in vivo magnetic resonance imaging”, Clouchoux, N. Guizard, A.C. Evans, A.J. DuPlessis, C. Limperopoulos, American Journal of Obstetrics and Gynecology, Vol. 206, No. 2. (12 February 2012), pp. 173.e1–173.e8, doi:10.1016/j.ajog.2011.10.002
  • “Cerebellar Malformations Alter Regional Cerebral Development”, M.E. Bolduc, A.J. du Plessis AJ, N. Sullivan, N. Guizard, X. Zhang, R.L. Robertson, C. Limperopoulos, Developmental medicine and child neurology, Vol. 53, No. 12. (8 December 2011), pp. 1128–1134, doi:10.1111/j.1469–8749.2011.04090.x
  • “Regional Cerebellar Volumes and Outcome”, M-E Bolduc, N. Guizard, C. Limperopoulos, Cerebellum (London, England) (7 September 2011), pp. 1–12, doi:10.1007/s12311–011–0312-z
  • “Robust 3D Reconstruction and Mean-Shift Clustering of Motoneurons from Serial Histological Images”, N. Guizard, P. Coupe, N. Stifani, S. Stifani, D. L. Collins, Medical Imaging and Augmented Reallity (MIAR), MICCAI, 2010, Proceedings, Beijing (Best paper award)pdf
  • “Cerebellar injury in the premature infant impairs growth of specific cerebral regions”, C. Limperopoulos, G. Chilingaryan, N. Guizard, R. L. Robertson, Pediatric research, Vol. 68, No. 2. (August 2010), pp. 145–150.
  • “Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy”: C. Limperopoulos, W. Tworetzky, DB. McElhinney, JW Newburger, D. Brown, R. Robertson, N. Guizard, E. McGrath, J. Geva, D. Annese, C. Dunbar-Masterson, B. Trainor, PC. Laussen, AJ. du Plessis, Circulation, Vol. 121, No. 1. (5 January 2010), pp. 26–33.

Submitted refereed papers:

Accepted or in press abstracts:

  • “Non-local MS MRI lesion inpainting method for image processing”, Nicolas Guizard, Kunio Nakamura, Pierrick Coupé, Douglas L. Arnold, D. Louis Collins, endMS conference, Saint-Sauveur, Canada, 2013
  • “Evaluation of Brain atrophy measurements methods: an MRI simulation study”, Kunio Nakamura, Nicolas Guizard, Vladimir S. Fonov, Sridar Narayanan, D. Louis Collins, Douglas L. Arnold, endMS conference, Saint-Sauveur, Canada, 2013 (Best paper award)
  • “Individual template creation with spatio-temporal regularization for longitudinal RRMS atrophy measure”, Nicolas Guizard, Vladimir Fonov, Doug L. Arnold, D. Louis Collins, ISMRM Multiple Sclerosis workshop, London, UK, 2013
  • “Pairwise Jacobian Integration Method to Measure Grey Matter Atrophy in Multiple Sclerosis.”, Kunio Nakamura, Nicolas Guizard, Vladimir Fonov, Sridar Narayanan, D. Louis Collins, Doug L. Arnold, ISMRM Multiple Sclerosis workshop, London, UK, 2013
  • “Brain growth rate is reduced in paediatric-onset multiple sclerosis”: B. Aubert-Broche, V. Fonov, N. Guizard, B. Banwell, S. Narayanan, D.L. Arnold, D.L. Collins, European committees for treatment and research in multiple sclerosis, Lyon, France, 2012
  • “4D non-linear registration for longitudinal analyses of ventricle enlargement in RRMS patients”, N. Guizard, M. Verin, V. Fonov, D. L. Arnold, D. L. Collins, European and Americas committees for treatment and research in multiple sclerosis, Amsterdam, Netherland, 2011
  • “BEaST: Brain extraction using multiresolution nonlocal segmentation”, S.F. Eskildsen, P. Coupe, K. K. Leung, V. Fonov, N. Guizard, S. N. Wassef, L.R. Østergaard, D.L. Collins, and the Alzheimer’s Disease Neuroimaging Initiative, Multi-Atlas Labeling and Statistical Fusion, Medical Image Computing and Computer Assisted Intervention Conference (MICCAI), Toronto, Canada, 2011
  • “Robust fusion of Jacobian maps for Deformation-Based Morphometry”, N. Guizard, P. Coupé, V. Fonov, D.L. Arnold, D.L. Collins, Organization for of Human Brain mapping (OHBM), June 2011, Québec, Canada
  • “Validation of basal ganglia segmentation on a 3T MRI Template”, C. Haegelen, N. Guizard, P. Coupé, F. Lalys, P. Jannin, X. Morandi, D.L. Collins, OHBM, June 2011, Québec, Canada
  • “Impact of NonLinear Registration Symmetry in Longitudinal MRI Studies”, N. Guizard, V. Fonov, B. Aubert-Broche, D. Louis Collins, submitted to Spatio Temporal Image Analyses (STIA), Medical Image Computing and Computer Assisted Intervention Conference (MICCAI), 2010, Beijing
  • “4-D In Vivo Fetal MRI Brain Atlas”, M. Bouyssi-Kobar, C. Clouchoux, N. Guizard, C. Limperopoulos, Young Europeen Scientist Meeting, Lisbon, 2010.
  • “A novel approach for high-resolution image reconstruction for in-vivo fetal brain MRI”, C. Clouchoux, P. Coupé, J. Manjon, N. Guizard, M. Bouyssi-Kobar, M. Lefebvre, A. Plessis, A. Evans, C. Limperopoulos, OHBM, June 2010, Barcelona, Spain
  • “Expression of the transcription factor RunX1 in spinal mortor neurons relevant to ALS”, N. Stifani, N. Guizard, D. L. Collins, S. Stifani, ALS Canada Sixth Annual Research Forum, 2010
  • “Symmetric Optimization Scheme versus Constrained Symmetrization for Non-Linear Registrations”, N. Guizard, V. Fonov, D. L. Collins, Medical Image Analysis on Multiple Sclerosis (MIAMS) Workshop, MICCAI, September 2009, London, UK
  • “Automatic Model-Based Fetal Brain Parcellation to Quantify In Vivo Fetal Brain Development”, N. Guizard, A.C. Evans, C. Lepage, A.J. du Plessis, C. Limperopoulos, NeuroImage, Vol. 47 (July 2009), pp. S87-S87.
  • “Fetal MRI Slice Reconstruction using 3D inpainting”, J. V. Manjón, N. Guizard, M. Robles, A. C. Evans, C. Limperopoulos, NeuroImage, Vol. 47 (July 2009), pp. S72-S72.
  • “Do regional reductions in cerebellar volume predict functional disabilities in children with cerebellar malformation?”, M. Bolduc, N. Guizard, A. du Plessis, R. Robertson, C. Limperopoulos, American Academy for Cerebral Palsy and Developmental Medicine (AACPDM), September 2008, Giorgia, USA
  • “Automatic Model-Based Fetal Brain Parcellation to Quantify In Vivo Fetal Brain Development”, N. Guizard, A.C. Evans, C. Lepage, A.J. du Plessis, C. Limperopoulos, Platform Presentation, Human Brain mapping (HBM), June 2009, San Francisco, USA
  • “Development of Fetus Brain Atlas from Multi-Axial MR Acquisitions”, N. Guizard, C. Lepage, V. Fonov, H. Hakyemez, A.C. Evans, C. Limperopoulos, Platform Presentation, International Society of Magnetic Resonance in Medicine (ISMRM), Volume 672. (2008) 132, May 2008, Toronto, Canada
  • “Dissociation of the role of the caudate nucleus and the dorsolateral prefrontal cortex in self-ordered and externally triggered monitoring tasks”, J.S. Provost, M. Petrides, N. Guizard, O. Monchi, Human Brain mapping (HBM), June 2007, Chicago, USA
  • “Role of the Caudate Nucleus in Executives Processes: an Eventrelated fMRI Study”, J.S. Provost, M. Petrides, N. Guizard, O. Monchi, 29e symposium international du Groupe de recherche sur le système nerveux central (GRSNC), May 2007, Montréal, Canada

Award:

  • International Society of Magnetic Resonance in Medicine (ISMRM): 300$US, 2013
  • European committee for treatment and research in multiple sclerosis (ECTRIMS): 600$CA, 2011
  • Fonds de recherche en nature et technologie: 20.000$CA/year for 3 years, 2011
  • MS society of Canada: 20.000$CA, 2011
  • Neuroinflamation travel award: 2000$CA, 2011
  • Neuroinflammation CIHR Strategic Training Program, 20.000$CA, 2009–2010
  • Graduate Research Enhancement and Travel Award (GREAT), McGill University, 500$CA, 2009
  • Human Brain Mapping (HBM) Trainee Abstract Award, 950$CA, 2009
  • Montreal Children’s Hospital (MCH) Studentship Travel Grant, 1.000$CA, 2009
  • McGill Graduate Entrance Award, 5.000$, 2008

Event organizer:

Personal projects: