Publications


Dedovic K, D’Aguiar C, Pruessner JC (in press). What stress does to your brain: a review of neuroimaging studies. Canadian Journal of Psychiatry, in press.

Dedovic K, Wadiwalla M, Engert V, Pruessner JC (in press). The role of gender in the development of stress-reactivity differences. Developmental Psychology, in press.

Fortin M. Voss P, Lord C, Lassonde M, Pruessner JC, Saint-Amour D, Rainville C, Le pore F (in press). Wayfinding in the blind: larger hippocampal volume and suporanormal spatial navigation. Brain, 2008 Oct 14, Epub ahead of print.

Pruessner M, Boekestyn L, Béchard-Evans L, Abadi S, Vracotas N, Joober R, Pruessner JC, Malla AK (in press). Sex differences in the cortisol response to awakening in recent onset psychosis. Psychoneuroendocrinology, 2008 Jul 18, epub ahead of print.

Vose P, Lord C, Maryse L, Pruessner JC, Saint-Amour D, Rainville C, Lepore F (in press). Wayfinding in the blind: larger hippocampal volume and supranormal spatial navigation. Brain, in press.

Lerch JP, Pruessner JC, Zijdenbos AP, Collins DL, Teipel SJ, Hampel H, Evan AC (2008). Automated cortical thickness measurement from MRI can accurately separate Alzheimer’s patients from normal elderly controls. Neurobiol Aging, 29(1), 23-30.

Lord C, Buss C, Lupien SJ, Pruessner JC (2008). Hippocampal volumes are larger in postmenopausal women using estrogen therapy compared to past users, never users and men: A possible window of opportunity effect. Neurobiology of Aging, 29(1), 95-101.

Loucks EB, Juster RP, Pruessner JC (2008). Neuroendocrine biomarkers, allostatic load, and the challenge of measurement: A commentary on Gersten. Social Science and Medicine, 66(3), 525-530.

Pruessner JC, Dedovic K, Khalili-Mahani N, Engert V, Pruessner M, Buss C, Renwick R, Dagher A, Meaney MJ, Lupien S (2008). Deactivation of the Limbic System during Acute Psychosocial Stress: Evidence from Positron Emission Tomography and Functional Magnetic Resonance Imaging Studies. Biol Psychiatry, 63(2), 234-240.

Quirin M, Pruessner JC, Kuhl J (2008). HPA system regulation and adult attachment anxiety: Individual differences in reactive and awakening cortisol. Psychoneuroendocrinology, 33(5), 581-590.

Soliman A, O’Driscoll GA, Pruessner JC, Holahan AL, Boileau I, Gagnon D, Dagher A (2008). Stress-induced dopamine release in humans at risk of psychosis: a [11C]raclopride PET study. Neuropsychopharmacology, 33(8), 2033-2041.

Wrosch C, Miller GE, Lupien S, Pruessner JC (2008). Diurnal cortisol secretion and 2-year changes in older adluts’ physical symptoms: The moderating roles of negative affect and sleep. Health Psychology, 27(6), 685-693.


Achim AM, Bertrand MC, Sutton H, Montoya A, Czechowska Y, Malla AK, Joober R, Pruessner JC, Lepage M (2007). Selective abnormal modulation of hippocampal activity during memory formation in first-episode psychosis. Arch Gen Psychiatry, 64(9), 999-1014.

Andrews J, Wadiwalla M, Juster RP, Lord C, Lupien SJ, Pruessner JC (2007). Effects of manipulating the amount of social-evaluative threat on the cortisol stress response in young healthy men. Behav Neurosci, 121(5), 871-876.

Bowles B, Crupi C, Mirsattari SM, Pigott SE, Parrent AG, Pruessner JC, Yonelinas AP, Kohler S (2007). Impaired familiarity with preserved recollection after anterior temporal-lobe resection that spares the hippocampus. Proc Natl Acad Sci U S A, 104(41), 16382-16387.

Buss C, Lord C, Wadiwalla M, Hellhammer DH, Lupien SJ, Meaney MJ, Pruessner JC (2007). Maternal care modulates the relationship between prenatal risk and hippocampal volume in women but not in men. J Neurosci, 27(10), 2592-2595.

Dandeneau SD, Baldwin MW, Baccus JR, Sakellaropoulo M, Pruessner JC (2007). Cutting stress off at the pass: reducing vigilance and responsiveness to social threat by manipulating attention. J Pers Soc Psychol, 93(4), 651-666.

Harvey PO, Pruessner J, Czechowska Y, Lepage M (2007). Individual differences in trait anhedonia: a structural and functional magnetic resonance imaging study in non-clinical subjects. Mol Psychiatry, 12(8), 703, 767-775.



Lupien SJ, Evans A, Lord C, Miles J, Pruessner M, Pike B, Pruessner JC (2007). Hippocampal volume is as variable in young as in older adults: implications for the notion of hippocampal atrophy in humans. Neuroimage, 34(2), 479-485.

Pruessner M, Pruessner JC, Hellhammer DH, Bruce Pike G, Lupien SJ (2007). The associations among hippocampal volume, cortisol reactivity, and memory performance in healthy young men. Psychiatry Res, 155(1), 1-10.

Shaw P, Lerch JP, Pruessner JC, Taylor KN, Rose AB, Greenstein D, Clasen L, Evans A, Rapoport JL, Giedd JN (2007). Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol, 6(6), 494-500.

Grabner G, Janke AL, Budge MM, Smith D, Pruessner JC, Collins DL (2006). Symmetric atlasing and model based segmentation: an application to the hippocampus in older adults. Med Image Comput Assist, 9(pt2): 58-66.

Teipel SJ, Pruessner JC, Faltraco F, Born C, Rocha-Unold M, Evans A, Moller HJ, Hampel H (2006). Comprehensive dissection of the medial temporal lobe in AD: measurement of hippocampus, amygdala, entorhinal, perirhinal, and parahippocampal cortices using MRI. J Neurol, 253(6), 794-800.

Parent C, Zhang T-Y, Caldji C, Bagot R, Champagne FA, Pruessner J & Meaney MJ (2005). Maternal Care and Individual Differences in Defensive Responses. Current Directions in Psychological Science, 14(5), 229-233.

Pruessner JC, Baldwin M, Dedovic K, Renwick R, Khalili Mahani N, Meaney M & Lupien S (2005). Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood. Neuroimage, 28(4), 815-826.

Lupien SJ, Schwartz G, Ng YK, Fiocco A, Wan N, Pruessner JC, Meaney MJ, Nair
NP (2005). The Douglas Hospital Longitudinal Study of Normal and
Pathological Aging: summary of findings. Journal of Psychiatry and Neuroscience, 30(5), 328-334.

Dedovic K, Renwick R, Mahani NK, Engert V, Lupien SJ, Pruessner JC (2005). The
Montreal Imaging Stress Task: using functional imaging to investigate the effects of perceiving and processing psychosocial stress in the human brain. Journal of Psychiatry and Neuroscience, 30(5), 319-325.

Corbo V, Clement M-H, Armony JL, Pruessner JC, Brunet A (2005). Size versus shape differences: contrasting voxel-Based and volumetric analyses of the anterior cingulate cortex in individuals with acute PTSD. Biological Psychiatry, 58(2), 119-124.

Hampel H, Burger K, Pruessner JC, Zinkowski R, DeBernardis J, Kerkman D,
Leinsinger G, Evans AC, Davies P, Moller HJ, Teipel SJ (2005). Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease. Arch Neurol, 62(5), 770-773.

Bouix S, Pruessner JC, Collins DL, and Siddiqi K (2005). Hippocampal shape analysis using medial surfaces. Neuroimage, 25(4), 1077-1089.

Lerch JP, Pruessner JC, Zijdenbos A, Hampel H, Teipel SJ, Evans AC (2004). Focal Decline of Cortical Thickness in Alzheimer's Disease Identified by computational Neuroanatomy. Cereb Cortex, 15(7), 995-1001.

Pruessner JC, Lord C, Meaney M, Lupien S (2004). Effects of self-esteem on age-related changes in cognition and the regulation of the hypothalamic-pituitary-adrenal axis. Ann N Y Acad Sci., 1032, 186-190.

Tisserand DJ, Van Boxtel M, Pruessner JC, Hofman P, Evans AC, Jolles J (2004). A voxel-based morphometric study to determine individual differences in gray matter density associated with age and cognitive change over time. Cerebral Cortex, 14(9), 966-973.

Pruessner JC, Champagne F, Meaney MJ, Dagher A (2004). Dopamine release in response to psychological stress in humans and its relationship to early life maternal care: a Positron Emission Tomography study using [11c]raclopride. Journal of Neuroscience, 24(11), 2825-2831.

Pruessner JC, Kirschbaum C, Meinlschmidt G, Hellhammer DH (2004). Other formulas for the computation of the area under the curve represent additional hormone concentration measures. Psychoneuroendocrinology, 29(4), 564-566.

Leinsinger G, Teipel S, Wismuller A, Born C, Meindl T, Flatz W, Schonberg S, Pruessner JC, Hampel H, Reiser M (2003). Volumetric MRI for evaluation of regional pattern and progression of neocortical degeneration in Alzheimer’s disease. Radiologe, 43(7), 537-542.

Pruessner JC, Kirschbaum C, Meinlschmid G, Hellhammer DH (2003). Two formulas for the computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology, 28(7), 916-931.

Pruessner M, Hellhammer D, Pruessner JC, Lupien S (2003). Self-reported depressive symptoms and stress levels in healthy young men: associations with the cortisol response to awakening. Psychosomatic Medicine, 65, 92-99.

Duchesne S, Pruessner J, Collins DL (2002). Appearance-based segmentation of medial temporal lobe structures. Neuroimage, 17, 515-531.

Pruessner JC, Collins D, Lemay M, Briere S, Pruessner M, Evans A, Meaney M, Lupien S (2002). Association between hypothalamic-pituitary-adrenal axis (HPA) function and frontal lobe volumes in elderly subjects with depressive symptoms and memory complaints. Brain and Cognition, 47, 176-179.

Pruessner JC, Kohler S, Crane J, Pruessner M, Lord C, Byrne A, Kabani N, Collins DL, Evans AC (2002). Volumetry of temporopolar, perirhinal, entorhinal and parahippocampal cortex from high-resolution MR images: considering the variability of the collateral sulcus. Cereb Cortex, 12, 1342-1353.

Tisserand DJ, Pruessner JC, Sanz Arigita EJ, van Boxtel MP, Evans AC, Jolles J, Uylings HB (2002). Regional frontal cortical volumes decrease differentially in aging: an MRI study to compare volumetric approaches and voxel-based morphometry. Neuroimage, 17, 657-669.

Wilner AP, de Varennes B, Gregoire PA, Lupien S, Pruessner JC (2002). Glucocorticoids and hippocampal atrophy after heart transplantation. Ann Thorac Surg, 73, 1965-1967.

Pruessner JC, Collins DL, Pruessner M & Evans AC (2001). Age and gender predict volume decline in the hippocampus in healthy males in early adulthood. Journal of Neuroscience, 21(1), 194-200.

Pruessner JC, Li LM, Serles W, Pruessner M, Collins DL, Kabani N, Lupien S & Evans AC (2000). Volumetry of Hippocampus and Amygdala with High-Resolution MRI and 3D analyzing software: Overcoming the discrepancies between laboratories. Cerebral Cortex, 10, 433-442.

Pruessner JC, Hellhammer DH & Kirschbaum C. (1999). Burnout, stress and cortisol responses to awakening in teachers. Psychosomatic Medicine, 61(2), 197-204.

Pruessner JC, Hellhammer DH & Kirschbaum C. (1999) Low self-esteem, induced failure and the adrenocortical stress response. Personality and Individual Differences, 27 (3), 477-489.

Schmidt-Reinwald A, Pruessner JC, Hellhammer DH, Federenko I., Rohleder N, Schürmeyer TH, & Kirschbaum C. (1999). The cortisol response to awakening in relation to different challenge tests and a 12-hour cortisol rhythm. Life Sciences, 64, 1653-1660.

Schulz P, Kirschbaum C, Pruessner JC & Hellhammer DH (1998). Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload. Stress Medicine, 14, 91-97.

Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum AB, vonAuer K, Jobst S, Kaspers F & Kirschbaum C (1997). Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical acitvity. Life Sciences, 61(26), 2539- 2549.

Pruessner JC, Gaab J, Hellhammer DH, Lintz D, Schommer N & Kirschbaum C (1997). Increasing correlations between personality traits and cortisol stress responses obtained by data aggregation. Psychoneuroendocrinology, 22(8), 615-625.

Kirschbaum C, Pruessner JC, Stone AA, Federenko I, Gaab J, Lintz D, Schommer N and Hellhammer DH (1995). Persistent high cortisol responses to repeated psychological stress in a subpopulation of healthy men. Psychosomatic Medicine, 57, 468-474.


Reviews, book chapters, books.


Engert V, Pruessner JC (in press). Developmental programming of dopamine regulation. In F Columbus (Ed), Dopamine Research Focus, Hauppage, NY, USA: Nova Science Publishers.

Pruessner JC, Wuethrich S, Baldwin M (in press). The stress of low self-esteem: On the relationship between personality factors and stress responsivity. In G Fink (Ed), Encyclopedia of Stress (2nd Edition), Oxford, UK: Elsevier.

Lord C & Pruessner JC (in press). Aging and adrenocortical factors. In G Fink (Ed), Encyclopedia of Stress (2nd Edition), Oxford, UK: Elsevier.

Pruessner JC (in press). Regulation of the Stress-response: Self-esteem and the stress response. In BS McEwen (Ed), New Encyclopedia of Neuroscience, Oxford, UK: Elsevier.

Lupien SJ, Ouellet-Morin I, Hupbach A, Walker D, Tu MT, Buss C, Pruessner J, McEwen BS (2006). Beyond the Stress Concept : Allostatic Load - A Development Biological and Cognitive Perspective. In D Cicchetti and DJ Cohen (Eds), Developmental Psychopathology Volume 2: Developmental Neuroscience (Ch. 14, pp 578-628). New Jersey, USA. John Wiley & Sons.

Pruessner JC, Hellhammer DH (2004). Psychosomatische Konzepte zu Burnout unter besonderer Beruecksichtigung von Untersuchungen an Lehrtaetigen [Psychosomatic concepts of Burnout with special attention to investigations in teachers]. In A Hillert (Hrsg.), Burnout bei Lehrtaetigen [Burnout in teachers] Stuttgart: Schattauer.

Pruessner JC, Lord C, Renwick R, Meaney M, Lupien S (2004). Age-related changes in the regulation of the Hypothalamic-Pituitary-Adrenal Axis: the role of personality hormones. In S Chanson et al (Eds), Endocrine Aspects of Successful aging: of genes, hormones, and lifestyles. Heidelberg: Springer.

Hampel H, Teipel SJ, Faltraco F, Pruessner JC & Buerger K (2003). Entwicklung von Positivkriterien zur Diagnose der Alzheimer-Demenz mithilfe bildgebender Verfahren und biologischer Marker - Perspektiven der Alzheimer-Forschung. [Development of positive criteria for the diagnosis of Alzheimer dementia using neuroimaging techniques and biological markers - Perspectives in the research of Alzheimer dementia] In H Hampel, F Padberg und HJ Moeller (Hrsg.), Alzheimer-Demenz. Klinische Verlaeufe, diagnostische Moeglichkeiten, moderne Therapiestrategien (S. 426 - 455). Stuttgart: Wissenschaftliche Verlagsgesellschaft.

Pruessner JC (1998). Freie Cortisolspiegel am Morgen: Untersuchungen zu Anstieg, Stabilitaet, soziodemographischen und psychologischen Variablen [Free cortisol levels after awakening: Investigations of increase, stability, and relations to sociodemographic and psychological variables]. Goettingen: Cuvillier Publishers.

Kirschbaum C, Wuest S, Pruessner JC & Hellhammer DH (1995). Psychischer Stress und Nebenniere: Psychoendokrinologische Befunde zur Beeinflussung der Kortisolreaktivitaet beim Menschen. [Psychological stress and the adrenal cortex: Psychoendocrinological factors determining cortisol reactivity in humans] In B Allolio, G Benker und HM Schulte (Hrsg.), Nebenniere und Stress. Von den Grundlagen zur Klinik (S. 131-138). Stuttgart: Schattauer.