fMRI Resources Available

MR Imaging Facilities

fMRI studies are conducted on the Centre's 1.5 Tesla Siemens Sonata scanner and 3 Tesla Siemens Trio scanner, using gradient echo EPI sequences. The scanners are operated by trained radiology technicians from the Montreal Neurological Institute. During the experiments, the technicians use preset fMRI sequences customized by BIC personnel. Some flexibility in these protocols is allowed and you are encouraged to consult us on protocol decisions when planning your study.


Stimulus Presentation and Subject Monitoring

Visual Stimulus

Equipment is in place for presenting visual stimuli or prompts using an LCD projector and mirror system. All of our projectors can display up to a 1024 x 768 pixel resolution and can be connected to a PC, Mac (or any other computer using a normal DB15 VGA connector), as well as VCRs and camcorders. The following image shows the types of connectors that can be used. DVI connectors, commonly found on Macbooks, are also compatible. However, if your Mac has a Mini Display port, Mini-DVI or Micro-DVI, please ensure that you bring your own VGA adapter as these connectors are currently not supported.

NEC 
Projector connectors

Projector connectors

In both of the BIC MR scanner rooms, we can project visual stimuli through either the front of the scanner bore, or the rear. In either setup, we have mirrors mounted inside the scanner bore which allow your subject to see the projected image on a movable screen outside the scanner.

Please note that the light coming out of the projector lens is extremely bright and is focused directly at the scanner patient table. Therefore, at the end of your scan always ensure that the projector is turned off before the projector screen is moved away from the front of the scanner. Otherwise, the high intensity light will be focused directly into your subject's eyes and you risk blinding them!

Stimulus Presentation

The stimulus presentation software is the responsibility of the experimenter. The software that we use, called GLStim, lacks advanced features that researchers often find necessary. There are commercially available experimental design programs which you can test and purchase. A few which have been used successfully here in the past are:

Audio Stimulus

The Siemens scanners are equipped with audio input capability. There is a 1/8 inch line in stereo jack in the equipment room, and beside the scanner console, where you can plug the line out of a PC sound card, laptop, CD player, tape recorder or any other audio device. If you use the audio input on the scanner, you must give your subject the Siemens headphones to hear the sound.

Subject Monitoring

Fiber-Optic Response Pad (fORP)

Our most popular device for subject feedback is a fiber optic response pad system which does not introduce any RF noise into the scanner room. This should also be your first option when considering input devices to use in our scanner. These USB devices are recognized by your computer as an external keyboard. We have several the response pads in several configurations; one of them is a 4-button device, with bottons arranged in a diamond shape. This one is a small 9x6cm plastic box with four color coded push buttons. The numeric characters 1, 2, 3, 4 are transmitted to your computer as keyboard presses of the following coloured buttons respectively: blue, yellow, green and red. The scanner trigger signal, which you will obtain with each scan, will be represented as a character 5 keyboard press. This setup has worked quite well for most experimenters. More information about the device can be found at Current Design's website http://www.curdes.com. The following picture shows what the 4 button diamond shaped fORP looks like with numbers drawn in above the corresponding button.

4 button fORP

The BIC also has a 2 button response pad and a bi-manual system for simultaneous right and left hand use with 4 buttons for each hand. The 2 button device delivers a '1' keyboard press for the blue button and a number '3' for a green button press. The scanner trigger signal is a '5' keyboard character press. Here is a picture of the 2-button device:

2 button fORP

The bi-manual fORP device has 4 buttons for each hand arranged in a curved line pattern. The right hand device delivers keyboard presses 1, 2, 3, 4 for the buttons colored blue, yellow, green and red respectively. The left hand device delivers 6, 7, 8, 9 for the blue, yellow, green and red button arrangement. The scanner trigger is always the number 5 keyboard press. Please keep in mind that both the left hand and right hand response pads must be used together.

bi-manual 8 button fORP


In case you are wondering how these different pieces of equipment are connected together, please look at the following diagram to give you a rough idea.

equipment setup

Equipment Setup


Image Transfers from the Scanner

Following an experiment, your images are transferred from the MR scanner computer to a directory on the BIC network. The technicians will execute the data transfer, and your images will be saved in MINC format in the following directory:

/data/transfer/minc

and in DICOM format in the following directory on any BIC network computer:

/data/transfer/dicom

The MINC images will remain in the transfer directory for seven days, after which they are permanently erased. The DICOM images also exist for seven days after the transfer from the scanner.

Please keep in mind that fMRI studies occupy large amounts of disk space and because the disks on the scanner console get filled very quickly, your images will be deleted from the scanner after a period of five (5) days. Therefore, the experimenter is responsible for notifying the technicians as soon as possible if there has been a problem with the image transfers. It is strongly recommended that you carefully verify your transfers, because sometimes they are completely or partially unsuccessful. If your transfer experienced problems, or your images have not appeared in /data/transfer/minc within 24 hours after your scan, please call the MR technicians at the MNI (tel. 514-398-6644 - ext: 0281) and they will attempt to resend your data.


The next sections walk you through the steps required to plan a study, book the scanner, perform the experiments, and analyze and interpret the data.





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