Proposed Project: Procedures

• exp4 Corticometric Studies of Developmental Pathology

  • exp4a Cross-Sectional Comparison of Patients with Schizophrenia and Normal Controls
    • Subjects: 159 pts (112 men, 47 women, mean age: 35.6 yr., SD 12.4) and 158 healthy sbs (106 men, 52 women, mean age: 37.7 yr., SD 14.0) from the Utrecht Schizophrenia Project, Utrecht, the Netherlands,
    • Methods: T1 wt. images were processed with CIVET, both native and standardized thickness was computed, and each subject's cortical thickness map was blurred using a 20 mm FWHM Gaussian smoothing kernel.
    • Statistical analysis (vertex-based) regressing cortical thickness vs. group, statistical maps were set to threshold: a) using the FDR procedure at a q value of 0.01, b) RFT at á value of 0.05.