Zhang (John) Chen

Office Phone: (514) 398-6174
Office Fax: (514) 398-8948
E-mail: zchen3@bic.mni.mcgill.ca
Mailing Address:

Welcome to my home page. I am a Ph.D student under the supervision of Dr. Alan C. Evans at the McConnell Brain Imaging Center of Montreal Neurological Institute, McGill University. I just submitted my thesis and expect to graduate in the summer. I am currently looking for post-doc position in the field of brain imaging.

My graduate work has focused on the characterization of normal and disease-specific human brain networks using morphological data from structural MRI. My main PhD thesis was to determine the modular architecture of brain networks using cortical thickness and this was applied to the aging and AD populations.

My research interests include developing multimodal imaging strategies of structural/functional brain network analysis and their applications in development, normal aging and brain disorders, such as Alzheimer's disease.


  1. Z J Chen, Y He, P Rosa-Neto, G Gong, A C Evans (2011) Age-related alterations in the modular organization of structural cortical network by using cortical thickness from MRI. Neuroimage, in press.
  2. Z J Chen, Y He, P Rosa-Neto, J Germann, A C Evans (2008) Revealing modular architecture of human brain structural networks by using cortical thickness from MRI. Cereb Cortex, 18: 10. 2374-81.
  3. B C Bernhardt, Z Chen, Y He, A C Evans, N Bernasconi, A Bernasconi (2011) Cross-sectional and longitudinal analyses demonstrate a cumulatively disrupted cortical network organization in temporal lobe epilepsy. Cereb Cortex, in press.
  4. L Fan, Y Tang, B Sun, G Gong, Z J Chen, X Lin, T Yu, Z Li, AC Evans, S Liu (2010) Sexual Dimorphism and asymmetry in human cerebellum: an MRI-based morphometric study. Brain Research, 1353:60-73.
  5. C Yan, G Gong, J Wang, D Wang, D Liu, C Zhu, Z J Chen, A C Evans, Y Zang, Y He (2010) Sex- and Brain Size-Related Small-World Structural Cortical Networks in Young Adultes: A DTI Tractography Study. Cereb Cortex, 21(2): 449-458.
  6. Y He, Z Chen, G Gong, A Evans (2009) Neuronal networks in Alzheimer's disease. Neuroscientist. 15(4): 333-50.
  7. Y He, A Dagher, Z Chen, A Charil, A Zijdenbos, K Worsley, A Evans (2009) Impaired small-world efficiency in structural cortical networks in multiple sclerosis associated with white matter lesion load. Brain 132(Pt 12): 3366-3379.
  8. G Gong, P Rosa-Neto, F Carbonell, J Chen, Y He, A Evans (2009) Age- and gender-related differences in the cortical anatomical network. J Neurosci. 29(50): 15684-15693.
  9. Y He, J Wang, L Wang, Z Chen, C Yan, H Yang, H Tang, C Zhu, Q Gong, Y Zang, A Evans (2009) Uncovering intrinsic modular organization of spontaneous brain activity in humans. PLoS ONE 4: (4). e5226.
  10. Fahim C, Yoon U, Das S, Lyttelton O, Chen J, Arnaoutelis R, Rouleau G, Sandor P, Frey K, Brandner C, Evans AC (2009). Somatosensory-motor bodily representation cortical thinning in Tourette: Effects of tic severity, age and gender. Cortex, 46(6): 750-760.
  11. J Wang, L Wang, Y Zang, H Yang, H Tang, Q Gong, Z Chen, C Zhu, Y He (2009) Parcellation-dependent small-world brain functional networks : A resting-state fMRI study. Hum Brain Mapp. 30: 5. 1511-1523.
  12. Y He, Z Chen, A Evans (2008) Structural insights into aberrant topological patterns of large-scale cortical networks in Alzheimer's disease. J Neurosci. 28: 18. 4756-66.
  13. A Evans, J Lee, S Kim, H Fukuda, R Kawashima, Y He, T Jiang, J Kim, Z Chen, K Im, O Lyttelton, J Lerch, V Singh, K Sato, Y Taki, R Goto, S Kinomura, K Mok, U Yoon (2008) Human cortical anatomical networks assessed by structural MRI. Brain Imaging and Behavior 2: 289-299.
  14. Y He, Z J Chen, A C Evans (2007) Small-world anatomical networks in the human brain revealed by cortical thickness from MRI. Cereb Cortex, 17: 10. 2407-19.

Publications (submitted/in preparation)

  1. Z J Chen, Y He, G Gong, P Rosa-Neto, LZ Fan, A C Evans (2011) Abnormal modular organization of structural cortical network in Alzheimer's disease. in revision.
  2. G Gong, Y He, Z Chen,, A C Evans (2011) Convergernce and divergence of thickness correlation with anatomical connectivity across the cerebral cortex. in preparation.

Conference oral presentation

  • Z J Chen,et. al., Abnormal modular organization of structural cortical network in Alzheimer's disease. 2010 AAN annual meeting, Toronto

  • Conference papers

  • John Chen, Jagath Samarabandu.Augmenting Range Data Obtained from Stereoscopy with Model-based Image Segmentation Using Planar Patches. IS&T/SPIE's Symposium on Electronic Imaging: Science & Technology, IS&T/SPIE 16th International Symposium, San Jose, California, USA, Jan. 2004.
  • John Chen, Jagath Samarabandu. Planar Region Depth Filling using Edge Detection with Embedded Confidence technique and Hough Transform. IEEE International Conference on Multimedia & Expo (ICME), Baltimore, USA, AIVP-P1: Image Processing I, 89-92, July 2003.


    Other Links

    John CHEN <zchen3@bic.mni.mcgill.ca>
    last modified: Feb. 2011