A number of processing steps are required to register two data sets
together. We have combined preprocessing steps (image intensity
non-uniformity correction [26], tube masking), linear
registration (
in linear mode [27]) and resampling into
stereotaxic space, cortical surface extraction (
[28,29]), tissue classification
(
[30]), automatic sulcal extraction (
[31]) and non-linear registration (
in nonlinear
mode [2]) into a processing pipeline.
After running this basic pipeline, a subject's MRI volume can be visualized
in stereotaxic space with its corresponding tissue labels, anatomical
structure labels, cortical surface and sulcal ribbons -- all in 3D. The
following sections describe the registration and sulcal extraction
procedures in more detail.