VERONIQUE BOHBOT, Ph.D.

Associate Professor, Department of Psychiatry
Associate Member, Department of Neurology and Neurosurgery
Faculty of Medicine, McGill University
Laboratory of Human Spatial Memory, Navigation and Functional Plasticity
Douglas Hospital Research Centre, FBC Building
6875 boul. LaSalle, Verdun, Quebec, Canada, H4H 1R3

Tucson, Arizona - where I obtained my Ph.D. with Dr. Lynn Nadel

Research

Our brains go through changes that are continuously renewing themselves as we experience the world. Research in my laboratory focuses on the multiple brain areas involved in processing episodic memories (spatio-temporal information) during navigation. We are interested in changes in the brain that occur as a result of practice or a learning experience. Multi-model aspects of memory, including visual, auditory, olfactory and proprioceptive aspects are being studied. Approaches include functional neuroimaging, neuroanatomy, neuropsychology, genetic and hormonal analyses with various populations that range from early development to senescence (patients with Epilepsy, Leukemia, Attention deficit hyperactivity disorder, Alzheimer's or Parkinson's disease). Applications are aimed at using multiple memory systems geared at rehabilitation techniques in patients with brain damage.

Projects and Techniques Available in my Laboratory

Example of a virtual environments created by Txomin viewed from the Unreal Editor

Examples of Virtual Environments created in my laboratory

Created by Txomin

Support

Students, Fellows and Staff

Alumni

Publications

  • Bohbot, V.D., Lerch, J., Thorndycraft, B., Iaria, G. & Zijdenbos, A. (2007) Gray matter differences correlate with spontaneous strategies in a human virtual navigation task. Journal of Neuroscience 27, 10078-10083. (200KB)

  • Bohbot, V.D. and Corkin, S. (2007) Parahippocampal place learning in H.M. Hippocampus, 17: 863-872. (300KB)

  • Etchamendy, N. and Bohbot, V.D. (2007) Spontaneous navigational strategies and performance in the virtual town. Hippocampus, 17: 595-599. (250KB)

  • Hupbach, A., Hardt, O., Nadel, L., and Bohbot, V. D. (2007) Spatial reorientation: Effects of verbal and spatial shadowing. Spatial Cognition & Computation 7: 213-226. (1,000KB)

  • Bohbot, V.D., Iaria, G., Petrides, M. (2004) Hippocampal function and spatial memory: Evidence from functional neuroimaging in healthy participants and performance of patients with medial temporal lobe resections. Neuropsychology 18(3):418-425. (200KB)

  • Stepankova K., Fenton A.A., Pastalkova E., Kalina M., Bohbot V.D. (2004) Object location memory impairment in patients with thermal lesions to the right or left hippocampus. Neuropsychologia, 42 (8): 1017-1028. (350KB)

  • Iaria, G., Petrides, M., Dagher, A., Pike, B., and Bohbot, V.D. (2003) Cognitive Strategies Dependent on the Hippocampus and Caudate Nucleus in Human Navigation: Variability and Change with Practice. J. Neuroscience, 23(13):5945-5952. (350KB)

  • Bohbot, V.D., Jech, R., Ruzicka, E., Nadel, L., Kalina, M., Stepankova, K. and Bures, J. (2002). Rat spatial memory tasks adapted for humans: characterization in subjects with intact brain and subjects with medial temporal lobe lesions. Physiological Research, 51 Suppl 1:S49-64. (716KB)

  • Nadel, L. and Bohbot, V.D. (2001) Consolidation of memory. Hippocampus, 11:56-60. (209KB)

  • Bohbot, V.D., Allen, J.J.B., and Nadel, L. (2000) Memory deficits characterized by patterns of lesions to the hippocampus and parahippocampal cortex. Annals of the New York Academy of Sciences, 911: 355-368. (6.4MB)

  • Johnsrude, I.S., Owen, A.M., White, N.M. Zhao, V.W., and Bohbot, V.D. (2000) Impaired preference conditioning after anterior temporal lobe resection in humans. Journal of Neuroscience, 20(7):2649-2656. (1 MB)

  • Bohbot, V.D., Kalina, M., Stepankova, K., Spackova, N., Petrides, and Nadel, L. (1998) Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex. Neuropsychologia, 36: 1217-1238. (23 MB)

  • Bohbot, V.D., Jech, R., Bures, J., Nadel, L., and Ruzicka, E. (1997) Spatial and non-spatial memory involvement in myasthenia gravis. Journal of Neurology, 244: 529-532. (1 MB)

  • Bohbot, V., Otahal, P., Liu, Z., Nadel, L., and Bures, J. (1996). Electroconvulsive shock and lidocaine reveal rapid consolidation of spatial working memory in the water maze. Proceedings of the National Academy of Sciences, 93: 4016-4019. (235 KB).

    Selected Posters & Data

  • Modulation of fMRI activation in hippocampus by spatial memory tested on a virtual radial-maze (343 KB). Society for Neuroscience Abstracts 2002, 475.10.

  • The collateral sulcus as a landmark for the parahippocampal cortex (page 1 of 2, 1.9 MB). NeuroImage.

  • The collateral sulcus as a landmark for the parahippocampal cortex (page 2 of 2, 1.9 MB). NeuroImage.

  • Verbal Reports. Bohbot et al., (2007) Journal of Neuroscience.
    E-mail:
    <veronique.bohbot@mcgill.ca>
    Office phone:
    (514) 761-6131, ext 4408
    Lab phone:
    (514) 761-6131, ext 3408
    Office fax:
    (514) 888-4099

    Links

    VERO <veronique.bohbot@mcgill.ca>
    last updated: 21 October 2004