Proposed Project: Procedures

• exp4 Corticometric Studies of Developmental Pathology

  • exp4b Childhood-Onset Schizophrenia vs. Controls: A Longitudinal Study
    • Children and adolescents were recruited by the NIMH for an ongoing study of childhood-onset schizophrenia,
    • 36 pts with COS (with onset of psychosis before age 12) and 34 healthy volunteers, age and gender matched, both groups having an age range of 8-24 years.
    • MR scans at a mean interval of around 2 years,
    • In the COS group, 19 patients had two, 12 had three, and five had four scans for a total of 94 scans.
    • In the normal control group, 19 subjects had two, 13 had three, and two had four scans, for a total of 85 scans.