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The Neuroimaging of Epilepsy Laboratory (NOEL) is part of the McConnell Brain Imaging Centre (BIC) of the Montreal Neurological Institute (MNI), a tertiary center that evaluates approximately 200 patients admitted each year for pre-surgical investigation of drug-resistant seizures. The BIC is an internationally recognized and multidisciplinary centre of excellence in neuroimaging research that is at the hub of a large group of investigators and trainees.

Our lab provides a unique environment fostering links between graduate students and postdoctoral fellows in Neuroscience, Computer Science, Engineering, and Neurology. This multidisciplinary environment has put NOEL in a unique position to generate a wide range of research perspectives and to develop novel methods of investigation that can directly impact the management and quality of care of patients with epilepsy.

Our research combines structural and functional MRI with statistical modeling. We use advanced morphometric (anatomical) and functional MRI (including resting-state fMRI) to assess cortical architecture, function, and plasticity in a search for endophenotypes and biomarkers of epileptogenesis. Main topics include automated lesion detection through computational modeling and machine learning, subcortical and cortical brain segmentation, analysis of brain networks based on graph-theoretical methods and independent component analysis. We are interested in tracking disease progression and its consequences on brain plasticity, connectivity and cognition.




Contact

Neuroimaging of Epilepsy Laboratory
McConnell Brain Imaging Center
Montreal Neurological Institute, WB 315
Montreal, Quebec, Canada
H3A 2B4
Phone: (514) 398-3361 or 4733
Fax: (514) 398-2975 or 8948
Email: click here