General exclusion criteria for Objectives 1 and 2

Below is a general overview of some exclusion criteria examples. Details can be found in the Objective 1 and 2 procedure manuals.

	Exclusion Categories	Examples
I	Demographic	Adopted, English fluency/Language, Parental history unknown
II	Pregnancy	Mother’s age at birth of child: <16 years or >44 years Exposure: Smoke & Alcohol (as specified in each manual), Medications & Drugs Medical: Preeclampsia, Anesthesia, Gestational diabetes
III	Delivery	Multiple births, Malpresention, Fetal distress, Forceps/Vacuum extraction
IV	Birth-neonatal	<37 weeks 4 days or >42 weeks 3 days, Growth (outside acceptable limits specified in manuals), AS<8@5m Seizures, Hyperbilia, Abnormal face/limbs, PKU, RDS, Infection
V	Child development	(below acceptable limits specified in manuals), non-English speaking, Breast-drugs Medical: Major medical illness, Congenital abnormalities, Heart problems, Cancer, Lead poisoning Neurological: Seizures, CNS Infection, Head injury, Significant hearing loss Intervention: Language disorder Psychiatric: Mood disorders, Conduct, AD/HD, Tics, Eating disorders
VI	Psychiatric – 1st degree	Bipolar, Chronic depression, Psychotic disorders, ADHD, Drug dependence, PDD
VII	Child testing/parental	Intelligence, Achievement, BSID & PLS-3 (<70), CBCL>70
VIII	Child neurological exam	Hyper/Hypo-tonia, Ocular motility, Face, Motor or reflex abnormalities, Tics